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Longevity and Science

Thinking about living well for longer can raise questions that feel both personal and scientific. These conversations explore what longevity means beyond a number, from everyday movement and social connection to sleep research and measurements of organ aging. David Stewart considers how fitness, resilience, and accessible habits fit into a fuller human experience. Dr. Nicole Moyen discusses temperature regulation, menopause, and the questions researchers are asking about sleep quality. Paul Coletta introduces proteomics and explores how biological measurements might guide action and track responses. Along the way, the discussions ask what health data can tell us, what remains uncertain, and how to distinguish useful information from the appeal of optimization. There is room here for curiosity about everyday life too.

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Latest conversations

Dr. Florence Comite - Groq Health & Reverse Aging For The Masses53 min

longevity

Dr. Florence Comite - Groq Health & Reverse Aging For The Masses

Dr. Florence Comite

Dan Freed - Thesis & The Rise of Nootropics43 min

longevity

Dan Freed - Thesis & The Rise of Nootropics

Dan Freed

Scott Burgett & Andy Beckman - Garmin & The Future of Digital Health50 min

tech

Scott Burgett & Andy Beckman - Garmin & The Future of Digital Health

Andy Beckman

Michael Chapp - Oura Ring: Better Tech, Better Sleep, Better Health49 min

tech

Michael Chapp - Oura Ring: Better Tech, Better Sleep, Better Health

Michael Chapp

Dr. Stacy Sims - "Women Are Not Small Men"49 min

longevity

Dr. Stacy Sims - "Women Are Not Small Men"

Dr. Stacy Sims

Jeff Byers - Momentous & Expert-Driven Protocols49 min

capital

Jeff Byers - Momentous & Expert-Driven Protocols

Jeff Byers

Miesha Tate - Lessons From a UFC Champ59 min

longevity

Miesha Tate - Lessons From a UFC Champ

Miesha Tate

Dr. Jeremy Koenig - DNA, Generative AI, & Gut Microbiomes54 min

tech

Dr. Jeremy Koenig - DNA, Generative AI, & Gut Microbiomes

Dr. Jeremy Koenig

Marcus Filly - The Modern Content Creator58 min

operators

Marcus Filly - The Modern Content Creator

Marcus Filly

Paul Byrne - The Cyclical Nature of The Fitness Industry53 min

capital

Paul Byrne - The Cyclical Nature of The Fitness Industry

Paul Byrne

Tony Gentilcore - The State of Coaching 202359 min

operators

Tony Gentilcore - The State of Coaching 2023

Tony Gentilcore

Eric Durak - The Past, Present, & Future of Medical Fitness52 min

longevity

Eric Durak - The Past, Present, & Future of Medical Fitness

Eric Durak

Kristen Holmes - Whoop 4.0 & The Future of Wearable Data Applications49 min

tech

Kristen Holmes - Whoop 4.0 & The Future of Wearable Data Applications

Kristen Holmes

Ryan DeLuca - Black Box VR & The State of VR Fitness45 min

tech

Ryan DeLuca - Black Box VR & The State of VR Fitness

Ryan DeLuca

John Klein - Pause Studios & Building a Wellness Lifestyle Brand50 min

operators

John Klein - Pause Studios & Building a Wellness Lifestyle Brand

John Klein

Andrew Herr - Fount & The Future of Performance Optimization46 min

longevity

Andrew Herr - Fount & The Future of Performance Optimization

Andrew Herr

Ari Tulla - Elo Health & "Smart Nutrition"50 min

tech

Ari Tulla - Elo Health & "Smart Nutrition"

Ari Tulla

Gilad Jacobs - Hyperice, NormaTec, & The Recovery Boom46 min

capital

Gilad Jacobs - Hyperice, NormaTec, & The Recovery Boom

Gilad Jacobs

Alexandra Zatarain - Eight Sleep & The Future of Sleep Technology45 min

tech

Alexandra Zatarain - Eight Sleep & The Future of Sleep Technology

Alexandra Zatarain

Eric Casaburi - Serotonin Centers & The Anti-aging Industry48 min

operators

Eric Casaburi - Serotonin Centers & The Anti-aging Industry

Eric Casaburi

Kevin Dawidowicz: CoachMePlus - Enterprise-Level Fitness50 min

tech

Kevin Dawidowicz: CoachMePlus - Enterprise-Level Fitness

Kevin Dawidowicz

Josh Bonhotal - Future.co & 1v1 Coaching At Scale56 min

tech

Josh Bonhotal - Future.co & 1v1 Coaching At Scale

Josh Bonhotal

Robert Louw - Wexer & The New Business Model of Fitness49 min

tech

Robert Louw - Wexer & The New Business Model of Fitness

Robert Louw

Jim Barr - Nautilus & The Future of Home Fitness54 min

capital

Jim Barr - Nautilus & The Future of Home Fitness

Jim Barr

Voices in the conversation

From the conversations

What outcome does David Stewart target in his training approach?

“I think that the difference here is that it's we're looking at the target is resilience. So durable capacity and if you're gonna talk about that then you sort of bring some other elements in here.”

David Stewart of Super Age at 67 and 11.4% Body Fat: What Real Longevity Looks Like · 28:06 ↗

Do researchers know exactly why people wake around 2:30 or 3 a.m.?

“The short answer is I don't think we have a clear understanding of exactly what causes that wake up. Um there's not one single answer, I should say.”

Dr. Nicole Moyen (Eight Sleep) on Temperature, Women's Sleep, and Menopause · 0:09 ↗

What does Paul Coletta mean by a closed loop health system?

“Bridging health insights or health data to targeted action. It needs to be actionable. And then here's the big part measuring the response, a validated health outcome. That's the closed loop system.”

The New Science of Aging: Why Your Organs Age at Different Rates with Paul Coletta · 12:17 ↗

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