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Longevity and Science

Thinking about living well for longer can raise questions that feel both personal and scientific. These conversations explore what longevity means beyond a number, from everyday movement and social connection to sleep research and measurements of organ aging. David Stewart considers how fitness, resilience, and accessible habits fit into a fuller human experience. Dr. Nicole Moyen discusses temperature regulation, menopause, and the questions researchers are asking about sleep quality. Paul Coletta introduces proteomics and explores how biological measurements might guide action and track responses. Along the way, the discussions ask what health data can tell us, what remains uncertain, and how to distinguish useful information from the appeal of optimization. There is room here for curiosity about everyday life too.

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Latest conversations

Jim LaValle - Peptides, GLP-1s, and the Product Problem: What Longevity Brands Are Missing58 min

longevity

Jim LaValle - Peptides, GLP-1s, and the Product Problem: What Longevity Brands Are Missing

Jim LaValle

John Ford - EGYM's Bet: The Untrained Market Is Where the Real Health Impact Is46 min

tech

John Ford - EGYM's Bet: The Untrained Market Is Where the Real Health Impact Is

John Ford

Mike Ranfone & Dr. Marko Lujic - The Gym of the Future Will Change the Future of Healthcare: RTS's Integration Model51 min

operators

Mike Ranfone & Dr. Marko Lujic - The Gym of the Future Will Change the Future of Healthcare: RTS's Integration Model

Chris Mirabile - Redefining Longevity: NOVOS, Healthspan, and What Really Works46 min

longevity

Chris Mirabile - Redefining Longevity: NOVOS, Healthspan, and What Really Works

Chris Mirabile

Mark Mastrov - The 24 Hour Fitness Acquisition: Mark Mastrov Returns with Long Range Capital52 min

capital

Mark Mastrov - The 24 Hour Fitness Acquisition: Mark Mastrov Returns with Long Range Capital

Mark Mastrov

Anthony Geisler's Sequel Brands: Five Boutique Brands, Zero Debt, 100% Control49 min

capital

Anthony Geisler's Sequel Brands: Five Boutique Brands, Zero Debt, 100% Control

Anthony Geisler's Sequel Brands

Garrett Salpeter - The NeuFit Framework: Nervous System First, Tissue Second50 min

longevity

Garrett Salpeter - The NeuFit Framework: Nervous System First, Tissue Second

Garrett Salpeter

Paul Byrne - The Consumer Health Revolution: Why GLP-1s, Biometrics, and AI Are Finally Converging52 min

longevity

Paul Byrne - The Consumer Health Revolution: Why GLP-1s, Biometrics, and AI Are Finally Converging

Paul Byrne

Brian Le Gette - Ammortal & The Future of "Human Vibrancy"47 min

longevity

Brian Le Gette - Ammortal & The Future of "Human Vibrancy"

Brian Le Gette

Robb Wolf - Why Market-Based Healthcare Is Fitness's Next Big Opportunity61 min

longevity

Robb Wolf - Why Market-Based Healthcare Is Fitness's Next Big Opportunity

Robb Wolf

Dr. Nestor Rodriguez - From Academic Medicine to Telehealth Scale: Carbon World Health's Medical-Fitness Integration Model53 min

longevity

Dr. Nestor Rodriguez - From Academic Medicine to Telehealth Scale: Carbon World Health's Medical-Fitness Integration Model

Dr. Nestor Rodriguez

Dr. Ryan Greene - Monarch Athletic Clubs: Where Medicine Meets Movement - Fitness 2.046 min

operators

Dr. Ryan Greene - Monarch Athletic Clubs: Where Medicine Meets Movement - Fitness 2.0

Dr. Ryan Greene

Carl Daikeler - Beachbody to BODi: Content is King, Simplicity is Queen51 min

capital

Carl Daikeler - Beachbody to BODi: Content is King, Simplicity is Queen

Carl Daikeler

Jay Worthy - MyZone & The Future of Motivational Technology50 min

tech

Jay Worthy - MyZone & The Future of Motivational Technology

Jay Worthy

Colleen Lewis & Dr. Amy Lee - bluSONIL: Where Aesthetics Meets Longevity53 min

longevity

Colleen Lewis & Dr. Amy Lee - bluSONIL: Where Aesthetics Meets Longevity

Colleen Lewis

Dr. Andy Galpin - Why Performance Beats Longevity - and How to Coach Both62 min

longevity

Dr. Andy Galpin - Why Performance Beats Longevity - and How to Coach Both

Dr. Andy Galpin

Gray Cook -  Movement Health Is the Missing Vital Sign64 min

longevity

Gray Cook - Movement Health Is the Missing Vital Sign

Gray Cook

Reka Gobis - Connected: Health & Fitness Summit 202641 min

capital

Reka Gobis - Connected: Health & Fitness Summit 2026

Reka Gobis

Dr. Amy B. Killen - Hormone Optimization Therapy's & The Future of Women's Health44 min

longevity

Dr. Amy B. Killen - Hormone Optimization Therapy's & The Future of Women's Health

Dr. Amy B. Killen

Simon Sollberger & Rich Bayly - PEAR Health Labs: Building the Operating System for Population Wellness49 min

tech

Simon Sollberger & Rich Bayly - PEAR Health Labs: Building the Operating System for Population Wellness

Juliet Starrett & Alex Alimanestianu - Quarterly Reports: Peloton, Life Time, Planet Fitness, Garmin & The Business of Longevity90 min

capital

Juliet Starrett & Alex Alimanestianu - Quarterly Reports: Peloton, Life Time, Planet Fitness, Garmin & The Business of Longevity

Dr. Stacy Sims - Hormones, HRV, and Heavy Lifting: The Science of Training Women Over 4547 min

longevity

Dr. Stacy Sims - Hormones, HRV, and Heavy Lifting: The Science of Training Women Over 45

Dr. Stacy Sims

Paul Byrne - Navigating MAHA: The Future of Fitness in American Healthcare49 min

capital

Paul Byrne - Navigating MAHA: The Future of Fitness in American Healthcare

Paul Byrne

Rick Mayo - Strength First: Simplifying the Modern Fitness Prescription48 min

operators

Rick Mayo - Strength First: Simplifying the Modern Fitness Prescription

Rick Mayo

Voices in the conversation

From the conversations

What outcome does David Stewart target in his training approach?

“I think that the difference here is that it's we're looking at the target is resilience. So durable capacity and if you're gonna talk about that then you sort of bring some other elements in here.”

David Stewart of Super Age at 67 and 11.4% Body Fat: What Real Longevity Looks Like · 28:06 ↗

Do researchers know exactly why people wake around 2:30 or 3 a.m.?

“The short answer is I don't think we have a clear understanding of exactly what causes that wake up. Um there's not one single answer, I should say.”

Dr. Nicole Moyen (Eight Sleep) on Temperature, Women's Sleep, and Menopause · 0:09 ↗

What does Paul Coletta mean by a closed loop health system?

“Bridging health insights or health data to targeted action. It needs to be actionable. And then here's the big part measuring the response, a validated health outcome. That's the closed loop system.”

The New Science of Aging: Why Your Organs Age at Different Rates with Paul Coletta · 12:17 ↗

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