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Longevity and Science

Thinking about living well for longer can raise questions that feel both personal and scientific. These conversations explore what longevity means beyond a number, from everyday movement and social connection to sleep research and measurements of organ aging. David Stewart considers how fitness, resilience, and accessible habits fit into a fuller human experience. Dr. Nicole Moyen discusses temperature regulation, menopause, and the questions researchers are asking about sleep quality. Paul Coletta introduces proteomics and explores how biological measurements might guide action and track responses. Along the way, the discussions ask what health data can tell us, what remains uncertain, and how to distinguish useful information from the appeal of optimization. There is room here for curiosity about everyday life too.

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Latest conversations

Dr. Bob Gabbay - The Future of GLP-1s48 min

longevity

Dr. Bob Gabbay - The Future of GLP-1s

Dr. Bob Gabbay

Edward Hertzman - Athletech's Innovation Summit51 min

capital

Edward Hertzman - Athletech's Innovation Summit

Edward Hertzman

Tom Dowd - From Revamp to Rebrand: The F45 Renaissance50 min

operators

Tom Dowd - From Revamp to Rebrand: The F45 Renaissance

Tom Dowd

Sam O'Keefe - Unlocking the $150 Billion HSA/FSA Opportunity40 min

capital

Sam O'Keefe - Unlocking the $150 Billion HSA/FSA Opportunity

Sam O'Keefe

Darren MacDonald - The Future of Tonal47 min

capital

Darren MacDonald - The Future of Tonal

Darren MacDonald

David Knies - The 5 Forces Driving the Next Trillion Dollars in Wellness45 min

capital

David Knies - The 5 Forces Driving the Next Trillion Dollars in Wellness

David Knies

Dr. Gloria Winters - The YMCA's Vision for Preventative Healthcare46 min

longevity

Dr. Gloria Winters - The YMCA's Vision for Preventative Healthcare

Dr. Gloria Winters

Heather Dietrick - Outside Interactive: Inspire, Activate, Celebrate46 min

capital

Heather Dietrick - Outside Interactive: Inspire, Activate, Celebrate

Heather Dietrick

Dr. Noura Abul-Husn - 23andMe's Total Health: the Integration of AI and Genetics48 min

longevity

Dr. Noura Abul-Husn - 23andMe's Total Health: the Integration of AI and Genetics

Dr. Noura Abul-Husn

Bryan O'Rourke - The Intersection of Fitness, Technology, and Global Trends49 min

tech

Bryan O'Rourke - The Intersection of Fitness, Technology, and Global Trends

Bryan O'Rourke

Dan Garner - Vitality Blueprint & The Business of Bloodwork51 min

longevity

Dan Garner - Vitality Blueprint & The Business of Bloodwork

Dan Garner

Kyle Jones - iCRYO & The Future of Longevity Franchising49 min

operators

Kyle Jones - iCRYO & The Future of Longevity Franchising

Kyle Jones

Emma Barry - Gen Z & Massive Systemic Change56 min

capital

Emma Barry - Gen Z & Massive Systemic Change

Emma Barry

Brad Kearns - Rethinking Longevity-based Fitness Programming55 min

longevity

Brad Kearns - Rethinking Longevity-based Fitness Programming

Brad Kearns

Jenn Pishko - The CrossFit Medical Society46 min

longevity

Jenn Pishko - The CrossFit Medical Society

Jenn Pishko

Anders Varner - Barbell Shrugged & Rapid Health Optimization60 min

longevity

Anders Varner - Barbell Shrugged & Rapid Health Optimization

Anders Varner

Juliet Starrett, Alex Alimanestianu, & Special Guest Philipp Roesch-Schlanderer - Quarterly Report74 min

capital

Juliet Starrett, Alex Alimanestianu, & Special Guest Philipp Roesch-Schlanderer - Quarterly Report

Philipp Roesch-Schlanderer

Jeff Zwiefel - Life Time's Miora: An Elegant Longevity Offering56 min

longevity

Jeff Zwiefel - Life Time's Miora: An Elegant Longevity Offering

Jeff Zwiefel

Lou DeFrancisco - Lindora & Scaling GLP-1 Weight Loss Programs53 min

longevity

Lou DeFrancisco - Lindora & Scaling GLP-1 Weight Loss Programs

Lou DeFrancisco

Krissy Vann - All Things Fitness & Wellness53 min

capital

Krissy Vann - All Things Fitness & Wellness

Krissy Vann

Jim Crowell & Jason Crowe - Proof3 & "Longevity Fitness"52 min

capital

Jim Crowell & Jason Crowe - Proof3 & "Longevity Fitness"

Jim Donnelly - The Rise of Humanaut Health64 min

longevity

Jim Donnelly - The Rise of Humanaut Health

Jim Donnelly

Todd Durkin - "True Strength" & Impact X Fitness52 min

operators

Todd Durkin - "True Strength" & Impact X Fitness

Todd Durkin

Juliet Starrett & Alex Alimanestianu - Quarterly Earnings Reports & Opportunities In Women's Health74 min

capital

Juliet Starrett & Alex Alimanestianu - Quarterly Earnings Reports & Opportunities In Women's Health

Voices in the conversation

From the conversations

What outcome does David Stewart target in his training approach?

“I think that the difference here is that it's we're looking at the target is resilience. So durable capacity and if you're gonna talk about that then you sort of bring some other elements in here.”

David Stewart of Super Age at 67 and 11.4% Body Fat: What Real Longevity Looks Like · 28:06 ↗

Do researchers know exactly why people wake around 2:30 or 3 a.m.?

“The short answer is I don't think we have a clear understanding of exactly what causes that wake up. Um there's not one single answer, I should say.”

Dr. Nicole Moyen (Eight Sleep) on Temperature, Women's Sleep, and Menopause · 0:09 ↗

What does Paul Coletta mean by a closed loop health system?

“Bridging health insights or health data to targeted action. It needs to be actionable. And then here's the big part measuring the response, a validated health outcome. That's the closed loop system.”

The New Science of Aging: Why Your Organs Age at Different Rates with Paul Coletta · 12:17 ↗

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